![]() ![]() ![]() ![]() Tc-99m sestamibi imaging is typically performed using early and delayed images to take advantage of the fact that the thyroid gland discharges the radionuclide more rapidly than does the abnormal parathyroid gland. In contrast, parathyroid imaging does not appear to improve the outcome of a standard bilateral neck exploration when it is performed by an experienced operator on a patient who has not had previous parathyroid surgery. Tc-99m sestamibi appears to be the most sensitive and specific of these techniques and is commonly used to identify a parathyroid lesion in patients who are candidates for minimally invasive parathyroid surgery. Technetium-99m (Tc-99m) sestamibi with or without single photon emission computed tomography (SPECT), ultrasound (US), CT, and magnetic resonance imaging (MRI) all are noninvasive techniques that can detect enlarged or abnormally functioning parathyroid tissue. Levine, in Encyclopedia of Endocrine Diseases, 2004 Parathyroid Imaging ![]()
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